Thursday, March 22, 2018

NBME Content Outline - Renal/Urinary System



NBME Content Outline - Renal/Urinary System.
(Step 1 item writers are assigned questions to write using this outline)


9.1 Normal processes
9.1.1 embryonic development, fetal maturation, and perinatal changes
9.1.2 organ structure and function
9.1.2.1 kidneys, ureters, bladder, urethra
9.1.2.2 glomerular filtration and hemodynamics
9.1.2.3 tubular reabsorption and secretion, including transport processes
and proteins
9.1.2.4 urinary concentration and dilution
9.1.2.5 renal mechanisms in acid-base balance
9.1.2.6 renal mechanisms in body fluid homeostasis
9.1.2.7 micturition
9.1.3 cell/tissue structure and function
9.1.3.1 renal metabolism and oxygen consumption
9.1.3.2 hormones produced by or acting on the kidney
9.1.4 repair, regeneration, and changes associated with stage of life
9.2 Abnormal processes
9.2.1 infectious, inflammatory, and immunologic disorders
9.2.1.1 infectious disorders
9.2.1.1.1 upper urinary tract
9.2.1.1.2 lower urinary tract
9.2.1.2 inflammatory and immunologic disorders
9.2.1.2.1 glomerular disorders
9.2.1.2.2 tubular interstitial disease
9.2.2 traumatic and mechanical disorders
9.2.3 neoplastic disorders
9.2.3.1 primary
9.2.3.1.1 renal
9.2.3.1.2 urinary bladder and collecting system
9.2.3.2 metastases
9.2.4 metabolic and regulatory disorders
9.2.4.1 renal failure, acute and chronic
9.2.4.2 tubular and collecting duct disorders
9.2.4.3 renal calculi
9.2.5 vascular disorders
9.2.6 systemic diseases affecting the renal system
9.3 Principles of therapeutics
9.3.1 mechanisms of action, use, and adverse effects of drugs for treatment of
disorders of the renal and urinary system
9.3.1.1 diuretics, antidiuretic drugs
9.3.1.2 drugs and fluids used to treat volume, electrolyte, and acid-base
disorders
9.3.1.3 drugs used to enhance renal perfusion
9.3.1.4 anti-inflammatory, antimicrobial, immunosuppressive, and
antineoplastic drugs
9.3.1.5 drugs used to treat lower urinary tract system
9.3.2 other therapeutic modalities

9.4 Gender, ethnic, and behavioral considerations affecting disease treatment and
prevention, including psychosocial, cultural, occupational, and environmental
9.4.1 emotional and behavioral factors
9.4.2 influence on person, family, and society
9.4.3 occupational and other environmental risk factors
9.4.4 gender and ethnic factors

Wednesday, March 21, 2018

taco paco peco paco

phyiological deadspace

Vd = tidal volume x (paco2 - peco2)/paco2

Vd = taco paco peco paco